What does the "world's smallest computer" look like? The University of Michigan has produced a temperature-sensing "computer" with a size of 0.04 cubic millimeters, which is about one-tenth of IBM's record. Its volume is so small that, in contrast, a grain of rice looks so large that it is so sensitive that its transmissive LED may excite current in its circuit.
Size limitations force researchers to creatively reduce the effects of light. They switch from a diode to a switched capacitor and have to deal with the relative increase in electrical noise produced by operating on devices that use such small power.


The result is a sensor that can measure changes in very small areas, such as a group of cells in the body. Scientists suspect that tumors are slightly hotter than healthy tissue, but it is difficult to confirm this until now. This tiny device can check this statement and, if it turns out to be true, can assess the effectiveness of cancer treatment. The team also envisions helping diagnose glaucoma in the eye, monitoring biochemical processes, and even studying small snails.
This does have a full-featured processor (based on the ARM Cortex-M0+ design), but it loses all data when it loses power, just like IBM's. Nonetheless, this has pushed the limits of computing power and shows that almost invisible calculations may be relatively widespread in the near future.

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